Module Update: Analyzing the connectome of C. elegans

Date and Location

May 12, 2015 - 4:00pm
Network Science Lab, Bldg 434, Rm 122

Speaker

Axel Haaker
IGERT Trainee
Mechanical Engineering, UCSB

Abstract

Caenorhabditis elegans (C. elegans), a species of nonparasitic roundworm has enjoyed study for well over a century. A favorite due to its small size, the ease at which populations can be grown, and the fact that it is one of the simplest orgainisms with a nervous system, in 1998 C. elegans became the first multicellular organism to have its entire genome sequenced. More recently, in 2012, the worm became the first, and so far the only, organism to have its entire neuronal wiring diagram charted. This wiring diagram, or connectome, will be the centerpiece of the talk. The introduction will cover the process through which the connectome was charted. The remainder of the talk will focus on the Network Science research module on which Ayme and I are working this quarter.

The work we have done so far has been primarily concerned with replicating some of the more network-centric results presented by Varshney, Chen, Paniagua, et al. in 2011. The talk will close with a discussion of what we hope to achieve with the time remaining in the quarter.